Tolterodine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tolterodine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain problems , slow heartbeat, QT prolongation in the family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. Dry mouth, constipation, abnormal vision accommodation abnormalities urinary retention, and dry eyes are expected side effects of antimuscarinic agents. rabeprazole
This study was not designed to make direct statistical comparisons between drugs or dose levels. Several different medications have been approved to relieve the symptoms of urinary frequency and urgency. This information should not be used to decide whether or not to take Detrol or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Detrol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Detrol. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Detrol.
PO Use is not recommended. Discuss specific use of drug and side effects with patient as it relates to treatment. HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Or it could signal a health problem. Take tolterodine tartrate extended-release capsules exactly as prescribed. Your doctor will prescribe the dose that is right for you. Do not change your dose unless told to do so by your doctor. How should I take tolterodine tartrate extended-release capsules?
It can force you to avoid vacations, dinners out, and other social situations. You can even miss out on valuable time with family and friends because you're afraid your -- also called OAB -- will trigger at the wrong time and embarrass you. Do not change your dose unless told to do so by your doctor. Detrol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. You have trouble emptying your bladder also called "urinary retention".
According to the FDA, the study participants could understand the label information and use the drug appropriately. Dry mouth, constipation, abnormal vision accommodation abnormalities urinary retention, and xerophthalmia are expected side effects of antimuscarinic agents. If you take pramlintide with anticholinergic or antispasmodic medicines, it may slow down the movement of food through your stomach too much and you may develop low blood sugar. Symptoms of low blood sugar include chills, cold sweat, dizziness, drowsiness, shaking, rapid heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. Severe low blood sugar makes it hard to think clearly, drive a car, use heavy machinery, or do other risky activities where you could hurt yourself or others. These measures will help to protect the environment. Use and dose must be determined by your doctor. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Avoid cyclosporine, dihydroergotamine, ergotamine, fentanyl, pimozide, quinidine, sirolimus, and tacrolimus. Are allergic to DETROL or to any of its ingredients.
No dosage adjustments required for otherwise healthy geriatric patients. 1 17 18 See Geriatric Use under Cautions. It's also important to eat high-fiber foods, because may worsen the symptoms of syndrome. Your doctor will tell you how long your treatment with Detrusitol will last. All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine. International Painful Bladder Foundation: "The Urinary Tract and How It Works. QT interval was found to correlate with plasma concentration of tolterodine. There appeared to be a greater QTc interval increase in CYP2D6 poor metabolizers than in CYP2D6 extensive metabolizers after tolterodine treatment in this study. amoxil
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Side Effects List Tolterodine TARTRATE side effects by likelihood and severity. Pharmaceuticals Inc. March, 2005. Detrol is to be used only by the patient for whom it is prescribed. Do not share it with other people. Peginterferon Alfa-2b: May decrease the serum concentration of CYP2D6 Substrates. Peginterferon Alfa-2b may increase the serum concentration of CYP2D6 Substrates. BID, tolterodine 4 mg BID, and placebo. What are possible side effects of Detrol? Pramlintide: May enhance the anticholinergic effect of Anticholinergic Agents. These effects are specific to the GI tract. Glycopyrrolate Oral Inhalation: Anticholinergic Agents may enhance the anticholinergic effect of Glycopyrrolate Oral Inhalation. Liver impairment can significantly alter the disposition of tolterodine immediate-release. Sections or subsections omitted from the full prescribing information are not listed. THE COLOURS SHOWN ON THIS PROOF ARE FOR GENERAL REPRESENTATION PURPOSES ONLY. Juss JK, Radhamma AK, Forsyth DR. Tolterodine-induced hyponatraemia. Age Ageing. All medicines may cause side effects, but many people have no, or minor, side effects. Keep this leaflet. You may need to read it again. fepo.info erythromycin
Efficacy in the pediatric population has not been demonstrated. Of the 1120 patients who were treated in the four Phase 3, 12-week clinical studies of Detrol, 474 42% were 65 to 91 years of age. Anon. Detrol LA and Ditropan XL for overactive bladder. Med Lett Drugs Ther. Complete the What is a document? Who should not take DETROL? Tolterodine is extensively metabolized by the liver following oral dosing. The primary metabolic route involves the oxidation of the 5-methyl group and is mediated by the cytochrome P450 2D6 CYP2D6 and leads to the formation of a pharmacologically active 5-hydroxymethyl metabolite. Tolterodine may cause a condition that affects the rhythm QT prolongation. Tolterodine acts as a competitive antagonist of acetylcholine at postganglionic muscarinic receptors. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. Leaflet revision and issue date Ref. DETROL LA is 2 mg once daily. mebendazole price london
Neurological Tests. Diagnostic tests and procedures that help the doctor confirm or rule out the presence of a nerve disorder. Use with caution. The effects may be increased because of slower removal of the medicine from the body. Kane says, "because for the most part, a number of them basically have about the same effectiveness, but they have different patterns of side effects. Carry a source of glucose such as glucose tablets or gel, table sugar, honey, candy, orange juice, or non-diet soda with you to quickly raise your blood sugar level if it is too low. Let your doctor know that you are experiencing low blood sugar. Secretin: Anticholinergic Agents may diminish the therapeutic effect of Secretin. Management: Avoid using drugs with substantial anticholinergic effects in patients receiving secretin whenever possible. If such agents must be used in combination, monitor closely for a diminished response to secretin. Perhexiline: CYP2D6 Substrates may increase the serum concentration of Perhexiline. Perhexiline may increase the serum concentration of CYP2D6 Substrates. Keep Tolterodine Tartrate Tablets and all medicines out of the reach of children. Talk to your doctor about using tolterodine safely. astonin tablets money order online
QT interval for heart rate. Take mirabegron by mouth with or without food. Bladder relaxants don't cure overactive bladder, but they can relieve the symptoms. This drug can be taken with or without food. Diet modification. You should avoid any food that appears to irritate your bladder or acts as a diuretic. What are tolterodine tartrate extended-release capsules? Gastrointestinal Agents Prokinetic: Anticholinergic Agents may diminish the therapeutic effect of Gastrointestinal Agents Prokinetic. Available as tolterodine tartrate; dosage expressed in terms of the salt. Some clinicians recommend administering tolterodine tartrate in a consistent manner relative to food intake. Take DETROL LA capsules once a day with liquid. Swallow the whole capsule. One percent of patients treated with Tolterodine Tartrate Tablets discontinued treatment due to dry mouth. Mitotane: May decrease the serum concentration of CYP3A4 Substrates. Management: Doses of CYP3A4 substrates may need to be adjusted substantially when used in patients being treated with mitotane.
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If you took more than your prescribed dose of tolterodine tartrate extended-release capsules, call your doctor or poison control center, or go to the hospital emergency room. Your doctor may occasionally change your dose to make sure you get the best results. Do not increase your dose or take this medication more often than directed. Your condition will not improve any faster and your risk of serious side effects may be increased. cheap venlor pills uk
Michel MC. Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome. Expert Opin Pharmacother. Detrol Tablets are contraindicated in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. Detrol is also contraindicated in patients who have demonstrated hypersensitivity to the drug or its ingredients, or to fesoterodine fumarate extended-release tablets which, like Detrol, are metabolized to 5-hydroxymethyl tolterodine. DETROL and get emergency medical help right away. The 4 mg capsules are aqua blue with “7164” imprinted on the body and “TEVA” imprinted on the cap. naltrexone
Rentzhog L, Stanton SL, Cardozo L et al. Efficacy and safety of tolterodine in patients with detrusor instability: a dose-ranging study. Br J Urol. The 4 mg capsules are blue with symbol and 4 printed in white ink. This may cause an increase in tears. Tolterodine is rapidly absorbed; bioavailability is at least 77%. T max is within 1 to 2 h immediate release and 2 to 6 h ER. Food increases bioavailability approximately 53% of immediate-release tolterodine, but has no effect on ER tolterodine. Those side effects are not new, however. They had been noted in previous studies.
You should not use Detrusitol when you are pregnant. Damage to nerves that supply the bladder can lead to problems with bladder function, including frequent and sudden urges to urinate. You are allergic to DETROL LA or to any of its ingredients. order generic risedronate pharmacy otc